Hepatitis B Viral DNA : Detection Through PCR

Hepatitis B is a serious liver infection that causes inflammation (swelling and reddening) and can lead to liver damage. Hepatitis B virus (HBV) infection can cause cirrhosis (hardening or scarring), liver cancer and even death.

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There are two types of hepatitis B infection :

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ACUTE : An acute infection happens at the beginning, when you first get infected with hepatitis B. Many people are able to clear it from their bodies and recover.

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CHRONIC : If the infection is not cleared within six months or longer, then it is chronic hepatitis B. Chronic hepatitis B can lead to inflammation, serious, and possibly fatal, illnesses of cirrhosis of the liver and liver cancer. Treatment can slow disease progress, reduce the chance of liver cancer and increase the chances of surviving.

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HBV DNA Quantitative PCR At Sampurna Sodani Diagnostic Clinic :
Real-Time Quantitative Polymerase Chain Reaction (PCR) test for the detection of Hepatitis B Virus DNA in human serum or plasma, encompassing all eight HBV genotypes (A-H).

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• Sensitivity & limit of detection : 2.5 IU/ml.

• TAT  :  Same day to Maximum 24 hours.

• Sample type  :  Serum/ plasma

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PURPOSE :

1. Detection and quantification of hepatitis B virus (HBV) DNA in serum of patients with chronic HBV infection.
2. Monitoring disease progression in chronic HBV infection by differentiating between active and inactive disease states.
3. Monitoring response to anti-HBV therapy, allowing prompt modification of treatment among anti-HBe positive, HBsAg negative- anti-HBs positive patients.